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About LycoRed  
What is LycoRed?   |   Benefits   |   Disease Spectrum


There are various indications for use of LycoRed like cancer risk reduction, prostate cancer adjunctive treatment and as part of antioxidant treatment regime. A few of the indications are listed below:

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Prostate Cancers
Cardiovascular Diseases
Diabetes

Brain Tumour

Infertility
Preeclampsia

Menopausal Complications
Pre-cancerous Oral Lesions
Cataracts

Longevity

Immune Modulation
Alzheimer's disease

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Prostate Cancers

• Kucuk O, Sarkar FH, Sakr W, Djuric Z, Pollak MN, Khachik F, Li YW, Banerjee M, Grignon D, Bertram JS, Crissman JD, Pontes EJ, Wood Jr. DP. Phase II Randomized Clinical Trial of Lycopene Supplementation before Radical Prostatectomy . Cancer Epidemiology, Biomarkers & Prevention 10: 861-868, 2001. Read more.

• Ansari MS, Gupta NP, Hemal AK. Chemoprevention of carcinoma prostate: a review. Int Urol Nephrol. 34(2): 207-14, 2002. Read more.

• Ansari MS, Gupta NP. A comparison of lycopene and orchidectomy vs orchidectomy alone in the management of advanced prostate cancer. BJU Int. 92: 375-378, 2003.
Read more.

•  Ansari MS, Ansari S. Lycopene and prostate cancer . Future Oncol. 1(3): 425-30, 2005. Read more.

•  Ansari MS, Gupta NP. Lycopene: A novel drug therapy in hormone refractory metastatic prostate cancer. Urol Oncol. 22(5): 415-20,2004. Read more.

• Mohanty NK, Nayak R, Arora R and Malhotra V. Role of lycopene as chemopreventive in treatment of high-grade intraepithelial neoplasia (HGPIN). BJU Int (S 2) (94): 92-93, 2004. Read more.

•  Mohanty NK, Saxena S, Singh UP, Goyal NK, Arora R. Lycopene as chemopreventive agent in treatment of high-grade prostate intraepithelial neoplasia. Urol Oncol. 23(6): 383-5, 2005. Read more.

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Cardiovascular Diseases

•  Fuhrman B, Elis A, Aviram M. Hypocholesterolemic effect of lycopene and beta-carotene is related to suppression of cholesterol synthesis and augmentation of LDL receptor activity in macrophages. Biochem Biophys Res Commun 1997; 233: 658-662, 1997. Read more.

•  Arab L, Steck S. Lycopene and cardiovascular disease. Am J Clin Nutr 2000; 71:1691S-1695S; discussion 1696S-1697S, 2000. Read more.

•  Rissanen TH, Voutilainen S, Nyyssonen K, et al. Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study. Br J Nutr 2001;85:749-754, 2001. Read more.

•  Engelhard YN, Gazer B, Paran E , Natural antioxidants from tomato extract reduce blood pressure in patients with grade-1 hypertension: A double-blind, placebo-controlled pilot study. Am Heart J 151:100.e1-100.e6. 2006. Read more.

•  Krishanmani NC. Correlation of Plasma Lycopene Levels with Obstructive Coronary Artery Disease . IHJ 56: 381, 2004.
Read more.

•  Bansal P, Gupta SK, Ojha SK, Nandave M, Mittal R, Kumari S, Arya DS. Cardioprotective effect of lycopene in the experimental model of myocardial ischemia-reperfusion injury. Mol Cell Biochem. Apr 7, 2006 [Epub ahead of print] Read more.
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Diabetes

•  Agarwal SK, Sahni V, Singh NP, Anuradha S, Sikdar S, Gahlot A, Wadhw a A . Lycopene Supplementation in Losartan Treated Elderly Type 2 Diabetes Mellitus Patients with Microalbuminuria and its Effect on Endothelial Function Markers. JAPI 53: 233-234, 2005. Read more.

•  Gahlot A, Agarwal SK, Singh NP, Makwane UK, Mishra TK, Yadav A, Makhija A. Effects of Atorvastatin and Lycopene on Endothelial Function and Lipid Peroxidation in Normotensive Type 2 Diabetes Mellitus Patients with Microalbuminuria. JAPI 53: 233-234, 2005. Read more.

•  A Gahlot, SK Agarwal, NP Singh, UK Makwane, TK Misha, A Yadav, A Makhija. Effects of Atorvastatin and Lycopene on Endothelial Function and Lipid Peroxidation in Normotensive Type 2 Diabetes Mellitus Patients with Microalbuminuria. JAPI 53:233-234, 2005. Read more.

•  Sikdar S, Anuradha S, Singh NP, Prakash A, Agarwal SK. Serum Lycopene in Type 2 Diabetes with microalbuminuria and its correlation with endothelial dysfunction. IHJ 55:561-570 Abstract no 416, 2003. Read more.

•  Sikdar S, Agarwal SK, Prakash A, Anuradha S, Singh NP. Lycopene supplemenattion in Losartan treated normotensive Type 2 diabetes mellitus patients with microalbuminuria and its effect on endothalial function markers. JAPI 51:1163 Abstract no 51, 2003. Read more.
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Brain Tumour

•  Julka PK , Puri Tarun, Goyal Shikha, Rath GK. Role of lycopene and Phytonutrients alongwith radiotherapy and chemotherapy in malignant gliomas. ASCO Annual Meeting Proceedings. Journal of Clinical Oncology, 23, 16S (June 1 Supplement), 2005: 1561). Read more.

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Infertility

•  Kumar R, Gupta NP. Lycopene Therapy in Idiopathic male Infertility: Results of a Clinical Trial. Indian Journal of Urology, 16:27 -28,2001.
Read more.

•  Mohanty NK. Kumar S, Jha AK , Arora RP. Management of Idiopathic Oligoasthenospermia with Lycopene. Indian Journal of Urology , 18(1): 57-61,2001. Read more.

•  Gupta NP, Ansari MS. Lycopene therapy in idiopathic male infertility - a preliminary report. Int Urol Nephrol. 4(3): 369-72, 2002. Read more.

•  Gupta NP. Emerging role of lycopene in male infertility. 1 st Int Conf on health benefits of Lycopene 2003,USA. Read more.

•  Kotia N, Swarankar ML. Management of idiopathic oligoasthenospermia with lycopene. AICOG 2003. Read more.

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Preeclampsia

•  Palan PR, Mikhail MS, Romney SL. Placental and serum levels of carotenoids in preeclampsia. Obstet Gynecol 2001;98:459-462, 2001. Read more.

•  Sharma JB, Kumar Ashok, Kumar A, Malhotra M, Arora R, Prasad S and Batra S. Effect of lycopene on pre-eclampsia and intra-uterine growth retardation in primigravidas. Int J Gyn Obs 2003; 81(3):257-62, 2003. Read more.

• Sharma JB, Mittal S. Oxidative stress & Preeclampsia. Editorial ; Obs & Gynae 10(9), 2004. Read more.

• Sharma JB, Mittal S. Lower antioxidant levels may explain both preeclampsia and cancers. BMJ.com Rapid responses for Paltiel et al., 328(7445): 919-0, 2004. Read more.

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Menopausal Complications

•  Mishra R, Mittal S. AIIMS research finds fountain of youth in the humble tomato. Indian Express, March 20, 2004.
Read more.

•  Misra R et al. Double blind randomized placebo-controlled trial to investigate the effect of lycopene on lipid peroxidation and lipid profile in post-menopausal women. J Obs Gyn Res 32(3), 2006 (in Press).

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Pre-cancerous Oral Lesions

•  Singh MP, Krishannappa R, Bagewadi A and Keluskar V. Efficacy of oral Lycopene in the treatment of oral leukoplakia . Oral Oncology 40: 591-596, 2004. Read more.

•  Singh MP . Efficacy of oral Lycopene in the treatment of oral leukoplakia. HealthWorlds Asia 2004 Congress, Kuala Lumpur Sept 2-5, 2004. Read more.

•  Kumar A, Bagewadi A, Keluskar V, Singh MP. Efficacy of Oral Lycopene in Oral Submucous Fibrosis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007, 103(2): 207-13.

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Cataracts

•  Gale CR, Hall NF, Phillips DI, Martyn CN. Plasma antioxidant vitamins and carotenoids and age-related cataract. Ophthalmology 2001;108:1992-1998, 2001. Read more.

•  Mohanty I, Joshi S, Trivedi D, Srivastatva S, Gupta SK. Lycopene prevents sugar-induced morphological changes and modulates antioxidant status of human lens epithelial cells.
Br J Nutr 88: 347-354, 2002. Read more.

•  Gupta SK, Trivedi D, Srivastatva S, Joshi S, Halder N, Verma SD. Lycopene attenuates Oxidative Stress Induced Experimental Cataract Development: An In Vitro and In Vivo Study. Nutrition 19:791-799, 2003. Read more.

•  Trivedi D, Srivastava S, Gupta SK . Prevention of cataract development by lycopene: an experimental study. Indian Journal of Pharmacology 33(3):242, 2001. Read more.

Trivedi D, Mohanty I, Srivastava S, Gupta SK . Lycopene a natural antioxidant protects against cataractous changes in lens epithelial cells . Indian Journal of Pharmacology 33(3):241-242, 2001. Read more.

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Longevity

•  Gross MD, Snowdon DA. Plasma lycopene and longevity: findings from the Nun Study. FASEB J 2001;15:A400, 2001.
Read more.

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Immune Modulation

•  Watzl B, Bub A, Brandstetter BR, Rechkemmer G. Modulation of human T lymphocyte functions by the consumption of carotenoid-rich vegetables. Br J Nutr 1999;82:383-389, 1999.
Read more.

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Alzheimer's disease

•  Polidori MC, Mecocci P. Plasma susceptibility to free radical-induced antioxidant consumption and lipid peroxidation is increased in very old subjects with Alzheimer disease.
J Alzheimers Dis
2002;4:517-522, 2002. Read more.

•  Mecocci P, Polidori MC, Cherubini A, et al. Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer disease. Arch Neurol 2002;59:794-798, 2002. Read more.



Lots of clinically oriented research is available in various others diseases.

 
   
   


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